Exploration of Highly Electron-Rich Manganese Complexes in Enantioselective Oxidation Catalysis; a Focus on Enantioselective Benzylic Oxidation
نویسندگان
چکیده
The direct enantioselective hydroxylation of benzylic C–H bonds to form chiral alcohols represents a challenging transformation. Herein, we report on the exploration new biologically inspired manganese and iron...
منابع مشابه
Highly Enantioselective Oxidation of Nonactivated Aliphatic C–H Bonds with Hydrogen Peroxide Catalyzed by Manganese Complexes
Monosubstituted cycloalkanes undergo regio- and enantioselective aliphatic C-H oxidation with H2O2 catalyzed by biologically inspired manganese catalysts. The reaction furnishes the corresponding ketones resulting from oxidation at C3 and C4 methylenic sites (K3 and K4, respectively) leading to a chiral desymmetrization that proceeds with remarkable enantioselectivity (64% ee) but modest regios...
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ژورنال
عنوان ژورنال: Catalysis Science & Technology
سال: 2021
ISSN: ['2044-4761', '2044-4753']
DOI: https://doi.org/10.1039/d1cy01642c